ATP7B Antikörper (AA 1055-1354)

Produktnummer ABIN6137355

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ATP7B in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ATP7B Antikörper (AA 1055-1354) (ABIN6137355)

Target: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP7B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATP7B Antikörper

Bindungsspezifität: AA 1055-1354

Sequenz: SDAMTDHEMK GQTAILVAID GVLCGMIAIA DAVKQEAALA VHTLQSMGVD VVLITGDNRK TARAIATQVG INKVFAEVLP SHKVAKVQEL QNKGKKVAMV GDGVNDSPAL AQADMGVAIG TGTDVAIEAA DVVLIRNDLL DVVASIHLSK RTVRRIRINL VLALIYNLVG IPIAAGVFMP IGIVLQPWMG SAAMAASSVS VVLSSLQLKC YKKPDLERYE AQAHGHMKPL TASQVSVHIG MDDRWRDSPR ATPWDQVSYV SQVSLSSLTS DKPSRHSAAA DDDGDKWSLL LNGRDEEQYI

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1055-1354 of human ATP7B (NP_001230111.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ATP7B

Target: ATP7B (ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))

Andere Bezeichnung: ATP7B

Hintergrund: This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).,ATP7B,PWD,WC1,WD,WND,Cancer,Signal Transduction,Endocrine & Metabolism,ATP7B

Molekulargewicht: 133 kDa/145 kDa/155 kDa/157 kDa

Gen-ID: 540

UniProt: P35670

Pathways: Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process