APOC1 Antikörper (AA 1-83)

Produktnummer ABIN6137012

Der Kaninchen Polyklonal Anti-APOC1-Antikörper wurde für IHC validiert. Er ist geeignet, APOC1 in Proben von Human zu detektieren.

Kurzübersicht für APOC1 Antikörper (AA 1-83) (ABIN6137012)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APOC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-APOC1 Antikörper

Bindungsspezifität: AA 1-83

Sequenz: MRLFLSLPVL VVVLSIVLEG PAPAQGTPDV SSALDKLKEF GNTLEDKARE LISRIKQSEL SAKMREWFSE TFQKVKEKLK IDS

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human APOC1 (NP_001636.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Andere Bezeichnung: APOC1

Hintergrund: This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,APOC1,Apo-CI,ApoC-I,apo-CIB,apoC-IB,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Heart,Lipids,Fatty Acids,Lipoproteins/Apolipoproteins,Cardiovascular diseases,Heart disease,APOC1

Molekulargewicht: 9 kDa

Gen-ID: 341

UniProt: P02654

Pathways: Apoptose