EIF2S1 Antikörper (pSer51)
Kurzübersicht für EIF2S1 Antikörper (pSer51) (ABIN6136152)
Target
Alle EIF2S1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer51
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Phosphorylated Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human Phospho-EIF2S1 (S51).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
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Andere Bezeichnung
- EIF2S1
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Hintergrund
- The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2, MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A,EIF2S1,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Protein folding,Protein phosphorylation,RNA Binding,Translation Control,Translational Control_Regulation of eIF2,EIF2S1
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Molekulargewicht
- 36 kDa
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Gen-ID
- 1965
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UniProt
- P05198
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Pathways
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
Target
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