FYN Antikörper (pSer21)

Produktnummer ABIN6136086

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FYN in WB. Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für FYN Antikörper (pSer21) (ABIN6136086)

Target: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FYN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FYN Antikörper

Bindungsspezifität: pSer21

Sequenz: DGSLN

Kreuzreaktivität: Human

Produktmerkmale: Phosphorylated Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic phosphorylated peptide around S21 of human Phospho-Fyn-S21 (NP_002028.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-FYN Antikörper (ABIN6136086)

Nakanishi, Menju, Nishikawa, Takahashi, Miyata, Shikuma, Sowa, Imamura, Hamaji, Motoyama, Hijiya, Aoyama, Sato, Chen-Yoshikawa, Sonobe, Date: "The synergistic role of ATP-dependent drug efflux pump and focal adhesion signaling pathways in vinorelbine resistance in lung cancer." in: Cancer medicine, Vol. 7, Issue 2, pp. 408-419, (2018) (PubMed).

Details zu FYN

Target: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Andere Bezeichnung: FYN

Hintergrund: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.,FYN,SLK,SYN,p59-FYN,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cell Adhesion,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Protein phosphorylation,FYN

Molekulargewicht: 54 kDa/60 kDa

Gen-ID: 2534

UniProt: P06241

Pathways: JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling