HDAC2 Antikörper (Ser394)

Produktnummer ABIN5956848

Der Kaninchen Polyklonal Anti-HDAC2-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, HDAC2 in Proben von Human, Maus, Ratte und Affe zu detektieren.

Kurzübersicht für HDAC2 Antikörper (Ser394) (ABIN5956848)

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HDAC2 Antikörper

Bindungsspezifität: Ser394

Spezifität: D10Wsu179e,HD 2,HD2,HDAC 2,Hdac2,HDAC2,Histone deacetylase 2 (HD2),Histone deacetylase 2,OTTHUMP00000017046,OTTHUMP00000227077,OTTHUMP00000227078,RPD3,transcriptional regulator homolog RPD3,YAF1,YY1 associated factor 1,YY1 transcription factor binding protein,Yy1bp

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu HDAC2

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Andere Bezeichnung: HDAC2

Hintergrund: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.

Molekulargewicht: 55kDa

Gen-ID: 3066

UniProt: Q92769

Pathways: Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion