Filamin A Antikörper (Ser2152)

Produktnummer ABIN5956573

Dieses Anti-Filamin A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Filamin A in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für Filamin A Antikörper (Ser2152) (ABIN5956573)

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Filamin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Filamin A Antikörper

Bindungsspezifität: Ser2152

Spezifität: ABP 280,ABP-280,Actin-binding protein 280,Alpha filamin,Alpha-filamin,APBX,CSBS,CVD1,Endothelial actin binding protein,Endothelial actin-binding protein,Filamin 1,Filamin A alpha,Filamin A,Filamin-1,Filamin-A,FLN,FLN-A,FLN1,FLNA,FLNA,FMD,MNS,NHBP,Non muscle filamin,Non-muscle filamin,OPD,OPD1,OPD2,XLVD,XMVD

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human Filamin 1 around the non-phosphorylation site of Ser2152.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Andere Bezeichnung: FLNA

Hintergrund: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 281kDa

Gen-ID: 2316

UniProt: P21333

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location