TXNRD1 Antikörper (AA 161-647)

Produktnummer ABIN5776265

Produktdetails anti-TXNRD1 Antikörper

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Bindungsspezifität: AA 161-647

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TXNRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Immunogen: Recombinant human TXNRD1 (161-647aa) purified from E. coli

Klon: AT30F1

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Andere Bezeichnung: Thioredoxin Reductase 1/TRXR1 (TXNRD1 Produkte)

Hintergrund: TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.

NCBI Accession: NP_001087240

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis