TXNRD1 Antikörper (AA 161-647)
Kurzübersicht für TXNRD1 Antikörper (AA 161-647) (ABIN5776265)
Target
Alle TXNRD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 161-647
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Immunogen
- Recombinant human TXNRD1 (161-647aa) purified from E. coli
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Isotyp
- IgG2b kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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Andere Bezeichnung
- Thioredoxin Reductase 1/TRXR1
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Hintergrund
- TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
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NCBI Accession
- NP_001087240
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
Target
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