IDH1 Antikörper (AA 1-414)

Produktnummer ABIN5776197

Dieser Maus Monoklonal Antikörper detektiert spezifisch IDH1 in WB, ELISA, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IDH1 Antikörper (AA 1-414) (ABIN5776197)

Target: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IDH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AT25H10

Produktdetails anti-IDH1 Antikörper

Bindungsspezifität: AA 1-414

Verwendungszweck: Human Isocitrate Dehydrogenase 1/IDH1 antibody

Aufreinigung: Purified

Immunogen: Recombinant human IDH1 (1-414aa) purified from E. coli

Isotyp: IgG2a kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu IDH1

Target: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Andere Bezeichnung: Isocitrate Dehydrogenase 1/IDH1

Hintergrund: IDH1, also known as isocitrate dehydrogenase (IDHC) cytoplasmic enzyme, belongs to the isocitrate and isopropylmalate dehydrogenases family. This protein catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming alpha-ketoglutarate and CO2 in a two-step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of alpha-ketoglutarate. IDH1 is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle.

NCBI Accession: NP_005887

Pathways: Warburg Effekt