Fascin Antikörper (AA 1-493)
Kurzübersicht für Fascin Antikörper (AA 1-493) (ABIN5776189)
Target
Alle Fascin (FSCN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-493
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Immunogen
- Recombinant human FSCN1 (1-493aa) purified from E. coli
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Isotyp
- IgG2b kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Fascin (FSCN1)
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Andere Bezeichnung
- Fascin/FSCN1
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Hintergrund
- FSCN1 is an actin-bundling protein that provides rigidity to filopodial bundles to efficiently push the membrane forward during cytoskeleton remodeling and cell migration. Probably involved in the assembly of actin filament bundles present in microspikes, membrane ruffles, and stress fibers. And this protein is absent from most normal epithelia yet is upregulated in multiple forms of human carcinoma, where its expression correlates clinically with a poor prognosis. FSCN1 expression has been localized to neurons, glial cells, and endothelial cells.
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NCBI Accession
- NP_003079
Target
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