Der Maus Monoklonal Anti-Beclin 1-Antikörper wurde für WB, ELISA, IF, FACS und ICC validiert. Er ist geeignet, Beclin 1 in Proben von Human zu detektieren.
BECN1
Reaktivität: Human
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Target
Beclin 1 (BECN1)
(Beclin 1, Autophagy Related (BECN1))
Andere Bezeichnung
Beclin 1/BECN1
Hintergrund
Beclin-1 is a protein that in humans is encoded by the BECN1 gene. Beclin-1 is a mammalian ortholog of the yeast autophagy-related gene (Atg) 6 and BEC-1 in the C. elegans nematode. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Beclin-1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy.