YWHAE Antikörper (AA 1-255)

Produktnummer ABIN5776144

Der Maus Monoklonal Anti-YWHAE-Antikörper wurde für WB, ELISA, IF und ICC validiert. Er ist geeignet, YWHAE in Proben von Human zu detektieren.

Kurzübersicht für YWHAE Antikörper (AA 1-255) (ABIN5776144)

Target: YWHAE (14-3-3 epsilon (YWHAE))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser YWHAE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AT4F8

Produktdetails anti-YWHAE Antikörper

Bindungsspezifität: AA 1-255

Immunogen: Recombinant human14-3-3 epsilon (1-255aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu YWHAE

Target: YWHAE (14-3-3 epsilon (YWHAE))

Andere Bezeichnung: 14-3-3 epsilon

Hintergrund: The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 epsilon, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer.

NCBI Accession: NP_006752

Pathways: Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, M Phase