PA2G4 Antikörper (AA 1-394)

Produktnummer ABIN5776098

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PA2G4 in WB, ELISA, IF, FACS und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PA2G4 Antikörper (AA 1-394) (ABIN5776098)

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PA2G4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: AT5E7

Produktdetails anti-PA2G4 Antikörper

Bindungsspezifität: AA 1-394

Immunogen: Recombinant human PA2G4 (1-394aa) purified from E. coli

Isotyp: IgG1 kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu PA2G4

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Andere Bezeichnung: PA2G4

Hintergrund: PA2G4 may play a role in a ERBB3-regulated signal transduction pathway and seems be involved in growth regulation. This protein acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Also, this protein Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity, and binds RNA. The protein is associated with 28S, 18S and 5. 8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA, that may be involved in regulation of intermediate and late steps of rRNA processing, and may be involved in ribosome assembly. The protein mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity), and regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).

NCBI Accession: NP_006182

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades