NCR3 Antikörper (AA 19-138)
Kurzübersicht für NCR3 Antikörper (AA 19-138) (ABIN5776033)
Target
Alle NCR3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 19-138
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Verwendungszweck
- Human NKp30/NCR3 antibody
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Aufreinigung
- Purified
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Immunogen
- Recombinant human NCR3 (19-138aa) purified from E. coli
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Isotyp
- IgG1 kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing cycles
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
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Andere Bezeichnung
- NKp30/NCR3
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Hintergrund
- NCR3, also known as NKP30, is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
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NCBI Accession
- NP_001138939
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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