SOD1 Antikörper (AA 1-154)
Kurzübersicht für SOD1 Antikörper (AA 1-154) (ABIN5776029)
Target
Alle SOD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 1-154
-
Verwendungszweck
- Human SOD1/Cu-Zn SOD antibody
-
Aufreinigung
- Purified
-
Immunogen
- Recombinant human SOD1 (1-154aa) purified from E. coli
-
Isotyp
- IgG1 kappa
-
-
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freezing and thawing cycles
-
Lagerung
- 4 °C,-20 °C,-80 °C
-
Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
-
-
- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
-
Andere Bezeichnung
- SOD1/Cu-Zn SOD
-
Hintergrund
- Cu/Zn superoxide dismutase (SOD1), is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. SOD1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. Also over 100 distinct SOD1 inherited mutations have been identified in the familial form of amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear.
-
NCBI Accession
- NP_000445
-
Pathways
- Sensory Perception of Sound, Transition Metal Ion Homeostasis
Target
-