SOD1 Antikörper (C-Term)

Produktnummer ABIN2854826

Produktdetails anti-SOD1 Antikörper

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to SOD1 (superoxide dismutase 1, soluble)
SOD1 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Güteklasse: KO Validated

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SOD1. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: Rat brain , 293T , A431 , HeLa , HepG2

Validation: KO/KD, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.21 mg/mL

Buffer: 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-SOD1 Antikörper (ABIN2854826)

Chang, Fong, Tsai, Chang, Chou, Wu, Teng, Liu, Yuan, Chiu: "Exogenous C₈-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).

Details zu SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Andere Bezeichnung: superoxide dismutase 1 (SOD1 Produkte)

Synonyme: LOC692639 antikoerper, ALS antikoerper, ALS1 antikoerper, IPOA antikoerper, SOD antikoerper, hSod1 antikoerper, homodimer antikoerper, CG11793 antikoerper, Cu antikoerper, Cu-Zn SOD antikoerper, Cu/Zn SOD antikoerper, Cu/Zn sod antikoerper, Cu/Zn superoxide dismutase antikoerper, Cu/ZnSOD antikoerper, CuSOD antikoerper, CuZn SOD antikoerper, CuZn-SOD antikoerper, CuZn-SOD1 antikoerper, CuZnSOD antikoerper, Cu[2+]/Zn[2+]SOD antikoerper, Dmel\\CG11793 antikoerper, G antikoerper, Mn SOD antikoerper, SOD-1 antikoerper, SOD1 antikoerper, Sod-1 antikoerper, Sod1 antikoerper, To antikoerper, To-1 antikoerper, Zn SOD antikoerper, Zn Sod antikoerper, Zn-SOD antikoerper, ZnSod antikoerper, cSOD antikoerper, cSod antikoerper, dSOD1 antikoerper, l(3)108 antikoerper, l(3)68Af' antikoerper, l(3)G antikoerper, sod antikoerper, sod1 antikoerper, CU/ZN-SOD antikoerper, SODC antikoerper, DKFZP469M1833 antikoerper, B430204E11Rik antikoerper, Cu/Zn-SOD antikoerper, Ipo-1 antikoerper, Ipo1 antikoerper, SOD1L1 antikoerper, XSODB antikoerper, als antikoerper, als1 antikoerper, ipoa antikoerper, sod1-a antikoerper, ZSOD antikoerper, cuzn antikoerper, Cu/Zn superoxide dismutase antikoerper, superoxide dismutase 1 antikoerper, Superoxide dismutase 1 antikoerper, superoxide dismutase 1, soluble antikoerper, superoxide dismutase 1 S homeolog antikoerper, Superoxide dismutase [Cu-Zn] antikoerper, superoxide dismutase 1 L homeolog antikoerper, superoxide dismutase [Cu-Zn]-like antikoerper, superoxide dismutase [Cu-Zn] antikoerper, superoxide dismutase Sod1 antikoerper, SOD antikoerper, SOD1 antikoerper, Sod1 antikoerper, sod1 antikoerper, sod1.S antikoerper, sod-1 antikoerper, sod1.L antikoerper, LOC101451855 antikoerper, LOC101115136 antikoerper

Hintergrund: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Cellular Localization: Cytoplasm

Molekulargewicht: 16 kDa

Gen-ID: 6647

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis