Cathepsin S Antikörper (AA 17-331)

Produktnummer ABIN5775924

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Cathepsin S in WB, ELISA, ICC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Cathepsin S Antikörper (AA 17-331) (ABIN5775924)

Target: Cathepsin S (CTSS)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cathepsin S Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: AT1F9

Produktdetails anti-Cathepsin S Antikörper

Bindungsspezifität: AA 17-331

Immunogen: Recombinant human CTSS (17-331aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu Cathepsin S

Target: Cathepsin S (CTSS)

Andere Bezeichnung: Cathepsin S

Hintergrund: CTSS (Cathepsin S) is a lysosomal enzyme that belongs to the papain family of cysteine proteases. This protein is expressed by antigen presenting cells including macrophages, B-lymphocytes, dendritic cells and microglia. Moreover, CTSS is expressed in some epithelial cells. In contrast, cortical thymic epithelial cells do not express CTSS. Normal epidermal keratinocytes do not express CTSS. However, level of CTSS is elevated in psoriatic keratinocytes due to stimulation by proinflammatory factors. CTSS can function as an elastase over a broad pH range in alveolar macrophages.

NCBI Accession: NP_004070

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades