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CD80 Antikörper (PE)

CD80 Reaktivität: Maus FACS, IHC, IHC (fro) Wirt: Ratte Monoclonal RM80 PE
Produktnummer ABIN576900
  • Target Alle CD80 Antikörper anzeigen
    CD80
    Reaktivität
    • 151
    • 108
    • 46
    • 8
    • 6
    • 6
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 92
    • 81
    • 21
    • 20
    • 19
    • 2
    • 1
    Ratte
    Klonalität
    • 153
    • 80
    • 2
    Monoklonal
    Konjugat
    • 97
    • 19
    • 19
    • 15
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD80 Antikörper ist konjugiert mit PE
    Applikation
    • 138
    • 93
    • 69
    • 39
    • 38
    • 25
    • 14
    • 13
    • 13
    • 12
    • 11
    • 10
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.
    Aufreinigung
    Affinity purified
    Immunogen
    BCL1 cells expressing CD80.
    Klon
    RM80
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD80 Primärantikörper
  • Applikationshinweise
    Approved: Flo (1:1), IHC, IHC-Fr

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
    Kommentare

    Target Species of Antibody: Mouse

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Distilled Water.
    Konzentration
    Lot specific
    Buffer
    Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    4°C, avoid freezing.
  • Target
    CD80
    Andere Bezeichnung
    CD80 (CD80 Produkte)
    Hintergrund
    Name/Gene ID: CD80

    Synonyms: CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 Molecule, CTLA-4 counter-receptor B7.1
    Gen-ID
    941
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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