CD80 Antikörper (PE)
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- Target Alle CD80 Antikörper anzeigen
- CD80
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD80 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.
- Aufreinigung
- Affinity purified
- Immunogen
- BCL1 cells expressing CD80.
- Klon
- RM80
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD80 Primärantikörper
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- Applikationshinweise
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Approved: Flo (1:1), IHC, IHC-Fr
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. - Kommentare
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Target Species of Antibody: Mouse
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Distilled Water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- 4°C, avoid freezing.
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- Target
- CD80
- Andere Bezeichnung
- CD80 (CD80 Produkte)
- Hintergrund
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Name/Gene ID: CD80
Synonyms: CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 Molecule, CTLA-4 counter-receptor B7.1 - Gen-ID
- 941
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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