CD13 Antikörper (AA 288-295) (PE)

Produktnummer ABIN576340

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD13 in FACS, WB, IHC, ELISA, IHC (fro) und IP. Er zeigt eine Reaktivität gegenüber Human und Rhesusaffen.

Kurzübersicht für CD13 Antikörper (AA 288-295) (PE) (ABIN576340)

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Reaktivität: Human, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD13 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Produktdetails anti-CD13 Antikörper (PE)

Bindungsspezifität: AA 288-295

Spezifität: Recognizes human CD13 also known as aminopeptidase N. CD13 is a single pass type II glycosylated integral membrane protein with a predicted molecular mass of ~110 kD and an apparent molecular mass of ~150 kD expressed by granulocytes, monocytes, fibroblasts, endothelial cells and by myeloid leukaemia cells. CD13 acts as a major cell surface receptor for group 1 coronoviruses which bind to a critical sequence encompassing amino acid residues 288-295. CD13 functions as an enzyme, a metalloprotease present as both a membrane bound form and also a soluble aminopeptidase N. Inhibits infection of cells by human coronavirus but not hepatitis C virus and inhibits aminopeptidase N activity of the CD13 Molecule.

Aufreinigung: Protein A purified

Immunogen: Human AML cells.

Type of Immunogen: Cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo (1:1), IHC, IHC-Fr, IP, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled Water.

Konzentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD13

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Andere Bezeichnung: ANP / CD13

Hintergrund: Name/Gene ID: ANPEP
Subfamily: Metallopeptidase M1
Family: Exopeptidase

Synonyms: ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1

Gen-ID: 290

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones