PRKDC Antikörper

Produktnummer ABIN576237

Der Kaninchen Polyklonal anti-PRKDC Antikörper (ABIN576237) detektiert spezifisch PRKDC in WB, IHC, IP, IHC (p) und EMSA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Hamster.

Kurzübersicht für PRKDC Antikörper (ABIN576237)

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reaktivität: Human, Maus, Ratte, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKDC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Electrophoretic Mobility-Shift Assay (EMSA)

Produktdetails anti-PRKDC Antikörper

Spezifität: Recognizes the human DNA-dependent protein kinase catalytic subunit, also known as DNA-PKcs, DNPK1 or p460. DNA PKcs is a 4128 amino acid ~460 kD nuclear protein encoded by the PRKDC gene, acting as a molecular sensor for DNA damage. Mutation of the PRKDC gene can result in Immunodeficiency 26 with or without neurologic abnormalities.

Immunogen: Human DNA-PKcs fragment.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: GS, IHC, IHC-P (1:100), IP, WB (1:2000)

Usage: Immunohistology: This product requires heat mediated treatment of paraffin sections. We recommend the use of antigen unmasking fluid for this purpose. A two hour incubation with LS-C42724 is recommended.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Serum, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu PRKDC

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Andere Bezeichnung: PRKDC / DNA-PKcs

Hintergrund: Name/Gene ID: PRKDC
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: PRKDC, DNA-PK, DNAPK, DNPK1, HYRC, HYRC1, p350, Scid, XRCC7, DNA-PK catalytic subunit, DNA-PKcs, p460, DNA-dependent protein kinase catalytic subunit

Gen-ID: 5591

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response