TPX2 Antikörper
Kurzübersicht für TPX2 Antikörper (ABIN5711936)
Target
Alle TPX2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-TPX2 Purified
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Spezifität
- The mouse monoclonal antibody TPX2-01 recognizes the epitope EPFVPKKEKKS (aa 636-646 in human) of TPX2, a microtubule-associated intracellular critical regulator of mitosis, which is overexpressed in many types of tumors and is a marker of worse prognosis in various cancers.
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Kreuzreaktivität (Details)
- Human, Mouse, Rat
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Immunogen
- Human TPX2
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Isotyp
- IgG1
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anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (C-Term) antibody
TPX2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) antibodyKD Validated TPX2 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 25GB4765 unconjugated Recombinant Antibody
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) antibodyTPX2 Reaktivität: Human WB, IP, ICC, FACS, DB Wirt: Maus Monoclonal 3164C6a unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (AA 160-320) antibodyTPX2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) antibodyTPX2 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (AA 350-382) antibodyTPX2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB0559 unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (AA 1-220) antibodyTPX2 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 18D5 unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (C-Term) antibodyTPX2 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (Internal Region) antibodyTPX2 Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
anti-TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2) (AA 551-650) antibodyTPX2 Reaktivität: Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))
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Andere Bezeichnung
- TPX2
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Hintergrund
- TPX2 microtubule nucleation factor,TPX2 is a microtubule-associated protein, which is a critical regulator of mitosis. At the beginning of mitosis, TPX2 is released and plays a significant role in mitotic spindle formation and subsequent proper segregation of chromosomes during cell division. After completion of mitosis the TPX2 protein disappears, but has also role in DNA damage response. Its overexpression has been demonstrated in many types of carcinomas. TPX2 belongs to the markers of worse tumor prognosis. On the other hand, down-regulation of TPX2 can inhibit cancer cell proliferation, migration and invasion.,DIL2, HCTP4, REPP86
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Gen-ID
- 22974
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UniProt
- Q9ULW0
Target
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