IL2RG Antikörper (PE)

Produktnummer ABIN5710229

Produktdetails anti-IL2RG Antikörper (PE)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reaktivität: Human, Hund

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL2RG Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: The rat monoclonal antibody TUGh4 recognizes an extracellular epitope of CD132 (the common gamma chain), a 65-70 kDa type I transmembrane glycoprotein broadly expressed by most leukocytes.

Kreuzreaktivität (Details): Human, Canine (Dog)

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human CD132-transfected cell line

Klon: TUGh4

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Kommentare:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Andere Bezeichnung: CD132 (IL2RG Produkte)

Synonyme: Ab2-183 antikoerper, Cd132 antikoerper, CD132 antikoerper, CIDX antikoerper, IL-2RG antikoerper, IMD4 antikoerper, P64 antikoerper, SCIDX antikoerper, SCIDX1 antikoerper, [g]c antikoerper, gamma(c) antikoerper, gc antikoerper, interleukin 2 receptor subunit gamma antikoerper, interleukin 2 receptor subunit gamma L homeolog antikoerper, interleukin 2 receptor, gamma chain antikoerper, IL2RG antikoerper, il2rg.L antikoerper, Il2rg antikoerper

Hintergrund: Interleukin 2 receptor subunit gamma,CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.,common gamma chain, IL2RG, SCIDX, IMD4

Gen-ID: 3561

UniProt: P31785

Pathways: JAK-STAT Signalweg, Growth Factor Binding