IL18BP Antikörper (AA 29-193)

Produktnummer ABIN5708089

Dieses Anti-IL18BP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL18BP in WB und ELISA. Geeignet für Maus und Ratte.

Kurzübersicht für IL18BP Antikörper (AA 29-193) (ABIN5708089)

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL18BP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL18BP Antikörper

Bindungsspezifität: AA 29-193

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant mouse partial protein corresponding to amino acids T29-A193 was used as the immunogen for the Il18bp antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Il18bp antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture): 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Il18bp antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu IL18BP

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Andere Bezeichnung: Il18 binding protein

Hintergrund: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: Q9Z0M9