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NKX2-1 Antikörper

This anti-NKX2-1 antibody (ABIN5708025) is a Rabbit Monoclonal antibody detecting NKX2-1 in IHC (p). Suitable for Human, Mouse, Rat.
Produktnummer ABIN5708025

Kurzübersicht für NKX2-1 Antikörper (ABIN5708025)

Target

Alle NKX2-1 Antikörper anzeigen
NKX2-1 (NK2 Homeobox 1 (NKX2-1))

Reaktivität

  • 81
  • 39
  • 39
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 51
  • 31
Kaninchen

Klonalität

  • 43
  • 39
Monoklonal

Konjugat

  • 49
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NKX2-1 Antikörper ist unkonjugiert

Applikation

  • 45
  • 36
  • 27
  • 25
  • 24
  • 20
  • 8
  • 7
  • 6
  • 3
  • 2
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

NX2-1-1855R
  • Aufreinigung

    Purified

    Reinheit

    Protein A affinity chromatography

    Immunogen

    Recombinant protein was used as the immunogen for the recombinant NKX2.1 antibody.

    Isotyp

    IgG kappa
  • Applikationshinweise

    Optimal dilution of the recombinant NKX2.1 antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store the recombinant NKX2.1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • Target

    NKX2-1 (NK2 Homeobox 1 (NKX2-1))

    Andere Bezeichnung

    NKX2.1 / TTF1

    Hintergrund

    NKX2.1/TTF1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-NKX2.1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of NKX2.1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. NKX2.1 reactivity is also seen in thyroid malignancies.

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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