NAPSA Antikörper (AA 189-299)

Produktnummer ABIN5707672

Dieses Anti-NAPSA-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von NAPSA in IHC (p). Geeignet für Human.

Kurzübersicht für NAPSA Antikörper (AA 189-299) (ABIN5707672)

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NAPSA Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: NAPSA-1865R

Produktdetails anti-NAPSA Antikörper

Bindungsspezifität: AA 189-299

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: A recombinant fragment from the human protein (amino acids 189-299) was used as the immunogen for the recombinant Napsin A antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the recombinant Napsin A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant Napsin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu NAPSA

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Andere Bezeichnung: Napsin A

Hintergrund: Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis