PIK3CB Antikörper (N-Term)

Produktnummer ABIN5706834

Hersteller Produkt- Nr.: 600-401-gt8

Dieses Anti-PIK3CB-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PIK3CB in WB und ELISA. Geeignet für Human.

Kurzübersicht für PIK3CB Antikörper (N-Term) (ABIN5706834)

Target: PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3CB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PIK3CB Antikörper

Bindungsspezifität: N-Term

Hersteller Produkt- Nr.: 600-401-gt8

Hersteller: Rockland

Verwendungszweck: PIK3CB Antibody

Kreuzreaktivität (Details): This antibody is specific for human PIK3C beta protein.

Produktmerkmale: Synonyms: rabbit anti-PIK3CB antibody, rabbit anti-PI3K beta antibody, PKC3B. PKC3 beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, PI3-kinase subunit beta, PI3K-ß, PI3Kbeta, PtdIns-3-kinase subunit beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, PtdIns-3-kinase subunit p110-beta, p110beta, PIK3C1

Aufreinigung: Anti-PIK3C beta was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterilität: Sterile filtered

Immunogen:

Immunogen: This affinity purified PIK3C-ß antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an N-terminal region of human Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform.

Immunogen Type: Conjugated Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-PIK3C beta Antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 122.7 kDa in size corresponding to PI3K beta by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1.0 μg/mL

ELISA Dilution: 1:50,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.09 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu PIK3CB

Target: PIK3CB (Phosphoinositide-3-Kinase, Catalytic, beta Polypeptide (PIK3CB))

Andere Bezeichnung: PIK3CB

Hintergrund: Background: PIK3CB is a catalytic subunit of phosphoinositide-3-kinase beta. PIK3CB catalyzes the production of phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidylinositol-4,5-bisphosphate (PIP2). Growth factors and hormones trigger this phosphorylation event, which in turn coordinates cell growth, cell cycle entry, cell migration and cell survival. PTEN reverses this process. PI3K signaling pathway is constitutively activated in human cancers that have loss of function of PTEN. Furthermore, PI3KCB down regulation can suppress cell growth in malignant gliomas. Anti-PIK3C beta Antibody is suitable for researcher in Cancer, Immunology and Nuclear Signaling research.

Gen-ID: 5291

NCBI Accession: NP_006210

UniProt: P42338