TSG101 Antikörper
Kurzübersicht für TSG101 Antikörper (ABIN5706095)
Target
Alle TSG101 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Immunogen
- tumor susceptibility gene 101
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Isotyp
- IgG
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Applikationshinweise
- WB:1:200-1:2000,IP:1:200-1:2000,IHC:1:100-1:500,IF:1:10-1:100
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Kommentare
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09040(TSG101 antibody) at dilution of 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Haltbarkeit
- 12 months
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Andere Bezeichnung
- TSG101
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Hintergrund
- Synonyms:ESCRT I complex subunit TSG101, TSG10, TSG101, tumor susceptibility gene 101, VPS23 Background:The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
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Molekulargewicht
- 46kDa
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Gen-ID
- 7251
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UniProt
- Q99816
Target
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