ALKBH5 Antikörper

Produktnummer ABIN5705091

Produktdetails anti-ALKBH5 Antikörper

Target: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALKBH5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: alkB, alkylation repair homolog 5 (E. coli)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:200-1:1000

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00314(ALKBH5 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ALKBH5

Target: ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))

Andere Bezeichnung: ALKBH5 (ALKBH5 Produkte)

Hintergrund: Synonyms:ABH5, ALKBH5, FLJ20308, OFOXD, OFOXD1 Background:Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine(m6A) RNA, the most prevalent internal modification of messenger RNA(mRNA) in higher eukaryotes(PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA(in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron(PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export(PubMed:23177736). Required for spermatogenesis(By similarity).

Molekulargewicht: 51kDa

Gen-ID: 54890

UniProt: Q6P6C2