PEX19 Antikörper

Produktnummer ABIN5704133

Der Kaninchen Polyklonal Anti-PEX19-Antikörper wurde für WB, ELISA, IHC und IP validiert. Er ist geeignet, PEX19 in Proben von Human und Maus zu detektieren.

Kurzübersicht für PEX19 Antikörper (ABIN5704133)

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-PEX19 Antikörper

Immunogen: peroxisomal biogenesis factor 19

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:200-1:2000 IP : 1:200-1:1000 IHC : 1:20-1:200

Kommentare:

human heart tissue were subjected to SDS PAGE followed by western blot with FNab06329(PEX19 antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu PEX19

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Andere Bezeichnung: PEX19

Hintergrund: Synonyms:33 kDa housekeeping protein, D1S2223E, HK33, Peroxin 19, PEX19, PMP1, PMPI, PXF, PXMP1 Background:This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 35-40 kDa

Gen-ID: 5824

UniProt: P40855