STK4 Antikörper

Produktnummer ABIN5703955

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STK4 in WB, ELISA, IHC, IP und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für STK4 Antikörper (ABIN5703955)

Target: STK4 (serine/threonine Kinase 4 (STK4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-STK4 Antikörper

Verwendungszweck: STK4 antibody

Immunogen: serine/threonine kinase 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:500-1:5000 IP : 1:500-1:5000 IHC : 1:20-1:200 IF : 1:20-1:200

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab08339(STK4 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Andere Bezeichnung: STK4

Hintergrund:

Synonyms: Serine/threonine-protein kinase 4|Mammalian STE20-like protein kinase 1 (MST-1)|STE20-like kinase MST1|Serine/threonine-protein kinase Krs-2|Serine/threonine-protein kinase 4 37kDa subunit (MST1/N)|Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)|STK4|KRS2|MST1

Background: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Gen-ID: 6789

UniProt: Q13043

Pathways: Tube Formation