STK4 Antikörper (AA 385-415)
Kurzübersicht für STK4 Antikörper (AA 385-415) (ABIN3032542)
Target
Alle STK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 385-415
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Verwendungszweck
- MST1 Antibody (Mammalian STE20-like protein kinase 1)
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Kreuzreaktivität (Details)
- Expected species reactivity: Bovine
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 385-415 from the human protein was used as the immunogen for this MST1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the MST1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the MST1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- STK4 (serine/threonine Kinase 4 (STK4))
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Andere Bezeichnung
- MST1 (Mammalian STE20-Like Protein Kinase 1)
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Hintergrund
- MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
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UniProt
- Q13043
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Pathways
- Tube Formation
Target
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