DDX39B Antikörper

Produktnummer ABIN5703741

Dieses Anti-DDX39B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DDX39B in ELISA, IHC, WB und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für DDX39B Antikörper (ABIN5703741)

Target: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX39B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-DDX39B Antikörper

Immunogen: HLA-B associated transcript 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:500-1:5000,IP:1:200-1:2000,IHC:1:20-1:200

Kommentare:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09142(BAT1 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu DDX39B

Target: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Andere Bezeichnung: UAP56

Hintergrund: Synonyms:ATP dependent RNA helicase p47, BAT1, D6S81E, DDX39B, DEAD box protein UAP56, HLA B associated transcript 1, Spliceosome RNA helicase BAT1, UAP56 Background:This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and it also plays an important role in mRNA export from the nucleus to the cytoplasm. This gene belongs to a cluster of genes localized in the vicinity of the genes encoding tumor necrosis factor alpha and tumor necrosis factor beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on both chromosomes 6 and 11. Read-through transcription also occurs between this gene and the upstream ATP6V1G2 (ATPase, H+ transporting, lysosomal 13 kDa, V1 subunit G2) gene.

Molekulargewicht: 57kDa

UniProt: Q13838

Pathways: Ribonucleoprotein Complex Subunit Organization