Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freeze / thaw cycles.
Lagerung
-20 °C
Haltbarkeit
12 months
Target
BUB1
(Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
Andere Bezeichnung
BUB1
Hintergrund
Synonyms:BUB1L Background:This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.