FANCL Antikörper

Produktnummer ABIN5701881

Dieses Anti-FANCL-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FANCL in WB, ELISA und IHC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für FANCL Antikörper (ABIN5701881)

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-FANCL Antikörper

Verwendungszweck: FANCL antibody

Immunogen: Fanconi anemia, complementation group L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab03010(FANCL antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu FANCL

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Andere Bezeichnung: FANCL

Hintergrund:

Synonyms: E3 ubiquitin-protein ligase FANCL|Fanconi anemia group L protein|Fanconi anemia-associated polypeptide of 43 kDa (FAAP43)|RING-type E3 ubiquitin transferase FANCL|FANCL|PHF9

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.

Molekulargewicht: 41-43 kDa

Gen-ID: 55120

UniProt: Q9NW38

Pathways: DNA Reparatur