NAMPT Antikörper

Produktnummer ABIN5701421

Der Kaninchen Polyklonal Anti-NAMPT-Antikörper wurde für WB, ELISA, IHC und IP validiert. Er ist geeignet, NAMPT in Proben von Human, Ratte, Maus und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für NAMPT Antikörper (ABIN5701421)

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAMPT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-NAMPT Antikörper

Verwendungszweck: NAMPT antibody

Immunogen: nicotinamide phosphoribosyltransferase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:500-1:5000,IHC:1:20-1:200,IP:1:500-1:5000

Kommentare:

mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab09412( NAMPT Antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu NAMPT

Target: NAMPT (Nicotinamide phosphoribosyltransferase (NAMPT))

Andere Bezeichnung: NAMPT

Hintergrund:

Synonyms: Nicotinamide phosphoribosyltransferase (NAmPRTase, Nampt)|Pre-B-cell colony-enhancing factor 1 (Pre-B cell-enhancing factor)|Visfatin|NAMPT|PBEF|PBEF1

Background: Nicotinamide phosphoribosyltransferase(NAMPT) has two usual synonyms termed Visfatin and PBEF. Its primary role is to catalyze the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD, which is the rate limiting component in the mammalian NAD biosynthesis pathway. NAMPT is localized in cytoplasm and expressed in large amounts in bone marrow, liver tissue, and muscle tissues. NAMPT inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. NAMPT levels are altered in plasma of patients with type 2 diabetes mellitus(T2DM), and it is now evidenced that NAMPT may plays a role in lipid metabolism.

Molekulargewicht: 47kDa

UniProt: P43490