BACE1 Antikörper
Kurzübersicht für BACE1 Antikörper (ABIN5700343)
Target
Alle BACE1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Immunogen
- beta-site APP-cleaving enzyme 1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Kommentare
-
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00781(BACE1 antibody) at dilution of 1:500
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Haltbarkeit
- 12 months
-
-
- BACE1 (Beta-secretase 1 (BACE1))
-
Andere Bezeichnung
- BACE1
-
Hintergrund
- Synonyms:BACE, KIAA1149 Background:Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
-
Molekulargewicht
- 70-75 kDa
-
Gen-ID
- 23621
-
UniProt
- P56817
Target
-