MAP1LC3A Antikörper (AA 1-125)

Produktnummer ABIN5700262

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAP1LC3A in WB, ELISA, IHC, IF, IP und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für MAP1LC3A Antikörper (AA 1-125) (ABIN5700262)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP1LC3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-MAP1LC3A Antikörper

Bindungsspezifität: AA 1-125

Verwendungszweck: LC3 antibody

Immunogen:

Immunogen sequence: 1-125aa

Immunogen: microtubule-associated protein 1 light chain 3 beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Chloroquine treated HeLa cells were subjected to SDS PAGE followed by western blot with FNab04717(LC3 Antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.1 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Andere Bezeichnung: LC3

Hintergrund:

Synonyms: Microtubule-associated proteins 1A/1B light chain 3B|Autophagy-related protein LC3 B|Autophagy-related ubiquitin-like modifier LC3 B|MAP1 light chain 3-like protein 2|MAP1A/MAP1B light chain 3 B (MAP1A/MAP1B LC3 B)|Microtubule-associated protein 1 light chain 3 beta|MAP1LC3B|MAP1ALC3

Background: Map1LC3, also known as LC3, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. Three human Map1LC isoforms, MAP1LC3A, MAP1LC3B, and MAP1LC3C, undergo post-translational modifications during autophagy. And they differ in their post-translation modifications during autophagy. Map1LC3 also exists in two modified forms, an 18- kDa cytoplasmic form that was originally identified as a subunit of the microtubule-associated protein 1, and a 16- kDa form that is associated with the autophagosome membrane. This antibody can cross react with MAP1LC3A, MAP1LC3B, and MAP1LC3C.

Molekulargewicht: 16 kDa

Pathways: Autophagie