SSRP1 Antikörper

Produktnummer ABIN5699682

Dieses Anti-SSRP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SSRP1 in WB, IHC, ELISA und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SSRP1 Antikörper (ABIN5699682)

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-SSRP1 Antikörper

Immunogen: structure specific recognition protein 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab08250(SSRP1 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu SSRP1

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Andere Bezeichnung: SSRP1

Hintergrund: Synonyms:FACT80 Background:The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

Gen-ID: 6749

UniProt: Q08945

Pathways: Chromatin Binding