KCNK18 Antikörper

Produktnummer ABIN5698029

Dieses Anti-KCNK18-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KCNK18 in WB und ELISA. Geeignet für Human.

Kurzübersicht für KCNK18 Antikörper (ABIN5698029)

Target: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNK18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KCNK18 Antikörper

Verwendungszweck: KCNK18 antibody

Immunogen: potassium channel, subfamily K, member 18

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu KCNK18

Target: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Andere Bezeichnung: KCNK18

Hintergrund:

Synonyms: Potassium channel subfamily K member 18|TWIK-related individual potassium channel|TWIK-related spinal cord potassium channel|KCNK18|TRESK|TRIK

Background: Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. May function as background potassium channel that sets the resting membrane potential. Channel activity is directly activated by calcium signal. Activated by the G(q)-protein coupled receptor pathway. The calcium signal robustly activates the channel via calcineurin, whereas the anchoring of 14-3-3/YWHAH interferes with the return of the current to the resting state after activation. Inhibited also by arachidonic acid and other naturally occurring unsaturated free fatty acids. Channel activity is also enhanced by volatile anesthetics, such as isoflurane. Appears to be the primary target of hydroxy-alpha-sanshool, an ingredient of Schezuan pepper. May be involved in the somatosensory function with special respect to pain sensation(By similarity).

Molekulargewicht: 44 kDa

Gen-ID: 338567

UniProt: Q7Z418