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RPGR Antikörper (AA 13-338)

RPGR Reaktivität: Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5693297
  • Target Alle RPGR Antikörper anzeigen
    RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))
    Bindungsspezifität
    • 7
    • 5
    • 2
    • 1
    AA 13-338
    Reaktivität
    • 22
    • 9
    • 9
    Ratte
    Wirt
    • 22
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RPGR Antikörper ist unkonjugiert
    Applikation
    • 12
    • 11
    • 9
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Verwendungszweck
    Anti-RPGR Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-RPGR Antibody Picoband® (ABIN5693297). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Immunogen
    E. coli-derived human RPGR recombinant protein (Position: A13-F338).
    Isotyp
    IgG
    Top Product
    Discover our top product RPGR Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. "Entrez Gene: RPGR retinitis pigmentosa GTPase regulator". 2. Murga-Zamalloa CA, Atkins SJ, Peranen J, Swaroop A, Khanna H (Sep 2010). "Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration". Human Molecular Genetics. 19 (18): 3591-8.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))
    Andere Bezeichnung
    RPGR (RPGR Produkte)
    Hintergrund

    Synonyms: X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3

    Tissue Specificity: Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments.

    Background: X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

    Molekulargewicht
    113 kDa
    Gen-ID
    6103
    UniProt
    Q92834
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