Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

RPGR Antikörper (AA 13-338)

Dieses Anti-RPGR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RPGR in WB und ELISA. Geeignet für Ratte.
Produktnummer ABIN5693297

Kurzübersicht für RPGR Antikörper (AA 13-338) (ABIN5693297)

Target

Alle RPGR Antikörper anzeigen
RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Reaktivität

  • 24
  • 9
  • 9
Ratte

Wirt

  • 24
Kaninchen

Klonalität

  • 24
Polyklonal

Konjugat

  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RPGR Antikörper ist unkonjugiert

Applikation

  • 13
  • 13
  • 11
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 7
    • 6
    • 2
    • 1
    • 1
    AA 13-338

    Verwendungszweck

    Anti-RPGR Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-RPGR Antibody Picoband® (ABIN5693297). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogen

    E. coli-derived human RPGR recombinant protein (Position: A13-F338).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. "Entrez Gene: RPGR retinitis pigmentosa GTPase regulator". 2. Murga-Zamalloa CA, Atkins SJ, Peranen J, Swaroop A, Khanna H (Sep 2010). "Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration". Human Molecular Genetics. 19 (18): 3591-8.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

    Andere Bezeichnung

    RPGR

    Hintergrund

    Synonyms: X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3

    Tissue Specificity: Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments.

    Background: X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

    Molekulargewicht

    113 kDa

    Gen-ID

    6103

    UniProt

    Q92834
Sie sind hier:
Chat with us!