RPGR Antikörper (C-Term)

Produktnummer ABIN954582

Produktdetails anti-RPGR Antikörper

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Bindungsspezifität: AA 743-772, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to RPGR.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 743-772 amino acids from the C-terminal region of human RPGR

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Andere Bezeichnung: RPGR (RPGR Produkte)

Synonyme: xrpgr antikoerper, COD1 antikoerper, CORDX1 antikoerper, CRD antikoerper, PCDX antikoerper, RP15 antikoerper, RP3 antikoerper, XLRP3 antikoerper, orf15 antikoerper, Rp3h antikoerper, retinitis pigmentosa GTPase regulator antikoerper, retinitis pigmentosa GTPase regulator S homeolog antikoerper, Rpgr antikoerper, RPGR antikoerper, rpgr antikoerper, rpgr.S antikoerper, Bm1_19935 antikoerper, NAEGRDRAFT_80250 antikoerper

Hintergrund: This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.Synonyms: RP3, X-linked retinitis pigmentosa GTPase regulator, XLRP3

Molekulargewicht: 113387 Da

Gen-ID: 6103

NCBI Accession: NP_000319