RPGR Antikörper (C-Term)

Produktnummer ABIN954582

Der Kaninchen Polyklonal anti-RPGR Antikörper (ABIN954582) detektiert spezifisch RPGR in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für RPGR Antikörper (C-Term) (ABIN954582)

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-RPGR Antikörper

Bindungsspezifität: AA 743-772, C-Term

Spezifität: This antibody reacts to RPGR.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 743-772 amino acids from the C-terminal region of human RPGR

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Andere Bezeichnung: RPGR

Hintergrund: This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.Synonyms: RP3, X-linked retinitis pigmentosa GTPase regulator, XLRP3

Molekulargewicht: 113387 Da

Gen-ID: 6103

NCBI Accession: NP_000319