MUC6 Antikörper (AA 52-230)

Produktnummer ABIN5693243

Dieses Anti-MUC6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MUC6 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für MUC6 Antikörper (AA 52-230) (ABIN5693243)

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MUC6 Antikörper

Bindungsspezifität: AA 52-230

Verwendungszweck: Anti-Gastric Mucin/MUC6 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Gastric Mucin/MUC6 Antibody Picoband® (ABIN5693243). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human Gastric Mucin recombinant protein (Position: H52-R230).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Kwon, J.-A., Lee, S.-Y., Ahn, E.-K., Seol, S.-Y., Kim, M. C., Kim, S. J., Kim, S. I., Chu, I.-S., Leem, S.-H. Short rare MUC6 minisatellites-5 (sic) alleles influence susceptibility to gastric carcinoma by regulating gene expression. Hum. Mutat. 31: 942-949, 2010. 2. Toribara, N. W., Roberton, A. M., Ho, S. B., Kuo, W.-L., Gum, E., Hicks, J. W., Gum, J. R., Jr., Byrd, J. C., Siddiki, B., Kim, Y. S. Human gastric mucin: identification of a unique species by expression cloning. J. Biol. Chem. 268: 5879-5885, 1993.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu MUC6

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Andere Bezeichnung: MUC6

Hintergrund:

Synonyms: Mucin-6, MUC-6, Gastric mucin-6, MUC6

Tissue Specificity: Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct.

Background: Mucin 6, oligomeric mucus/gel-forming, also known as MUC6, is a human gene. This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract.

Molekulargewicht: 257 kDa

Gen-ID: 4588

UniProt: Q6W4X9