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APCS Antikörper (AA 20-220)

This anti-APCS antibody (ABIN5693182) is a Rabbit Polyclonal antibody detecting APCS in WB, IHC, ELISA, ICC, IF, FACS. Suitable for Human.
Produktnummer ABIN5693182

Kurzübersicht für APCS Antikörper (AA 20-220) (ABIN5693182)

Target

Alle APCS Antikörper anzeigen
APCS (Amyloid P Component, Serum (APCS))

Reaktivität

  • 78
  • 17
  • 13
  • 2
  • 1
Human

Wirt

  • 68
  • 26
  • 2
  • 1
Kaninchen

Klonalität

  • 71
  • 26
Polyklonal

Konjugat

  • 64
  • 10
  • 7
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser APCS Antikörper ist unkonjugiert

Applikation

  • 71
  • 60
  • 33
  • 28
  • 23
  • 8
  • 7
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 14
    • 12
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-220

    Verwendungszweck

    Anti-Serum Amyloid P/APCS Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Serum Amyloid P/APCS Antibody Picoband® (ABIN5693182). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogen

    E. coli-derived human Serum Amyloid P recombinant protein (Position: H20-L220).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
    Immunocytochemistry/Immunofluorescence, 5 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    ELISA, 0.1-0.5 μg/mL
    1. Cathcart ES, Shirahama T, Cohen AS (1967). "Isolation and identification of a plasma component of amyloid". Biochim. Biophy. Acta 147: 392-393. 2. "Entrez Gene: APCS amyloid P component, serum". 3. Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP (1994). "Structure of pentameric human serum amyloid P component". Nature 367 (6461): 338-45.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    APCS (Amyloid P Component, Serum (APCS))

    Andere Bezeichnung

    APCS

    Hintergrund

    Synonyms: Serum amyloid P-component; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P-component (1-203); APCS; PTX2

    Tissue Specificity: Found in serum and urine.

    Background: Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

    Molekulargewicht

    25-29 kDa

    Gen-ID

    325

    UniProt

    P02743
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