GNS Antikörper (AA 238-355)

Produktnummer ABIN5693115

Produktdetails anti-GNS Antikörper

Target: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Bindungsspezifität: AA 238-355

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for GNS detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human GNS recombinant protein (Position: W238-R355).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu GNS

Target: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Andere Bezeichnung: GNS (GNS Produkte)

Synonyme: G6S antikoerper, 2610016K11Rik antikoerper, AU042285 antikoerper, C87209 antikoerper, N28088 antikoerper, NV14559 antikoerper, N-acetylglucosamine-6-sulfatase antikoerper, zgc:114066 antikoerper, gns antikoerper, wu:fi20h10 antikoerper, zgc:55370 antikoerper, glucosamine (N-acetyl)-6-sulfatase antikoerper, glucosamine (N-acetyl)-6-sulfatase S homeolog antikoerper, glucosamine (N-acetyl)-6-sulfatase a antikoerper, N-acetylglucosamine-6-sulfatase antikoerper, glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b antikoerper, GNS antikoerper, Gns antikoerper, gns.S antikoerper, gns antikoerper, gnsa antikoerper, CpipJ_CPIJ000745 antikoerper, Sros_7372 antikoerper, VDBG_04409 antikoerper, Halhy_3165 antikoerper, gnsb antikoerper

Hintergrund:

Synonyms: N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS

Background: N-acetylglucosamine-6-sulfatase, also known as glucosamine (N-acetyl)-6-sulfatase, is an enzyme that in humans is encoded by the GNS gene. The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

UniProt: P15586

Pathways: Glycosaminoglycan Metabolic Process