MYBPC3 Antikörper (AA 1070-1123)
Kurzübersicht für MYBPC3 Antikörper (AA 1070-1123) (ABIN5693035)
Target
Alle MYBPC3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- AA 1070-1123
- 
                                            Verwendungszweck
- Anti-MYBPC3 Antibody Picoband®
- 
                                            Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
- 
                                            Produktmerkmale
- Anti-MYBPC3 Antibody Picoband® (ABIN5693035). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 
                                            Immunogen
- E. coli-derived human MYBPC3 recombinant protein (Position: Q1070-H1123).
- 
                                            Isotyp
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            Applikationshinweise
- 
                        Western blot, 0.1-0.5 μg/mL
 Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
 ELISA, 0.1-0.5 μg/mL
 1. Calore, C., De Bortoli, M., Romualdi, C., Lorenzon, A., Angelini, A., Basso, C., Thiene, G., Iliceto, S., Rampazzo, A., Melacini, P. A founder MYBPC3 mutation results in HCM with a high risk of sudden death after the fourth decade of life. J. Med. Genet. 52: 338-347, 2015. 2. Ehlermann, P., Weichenhan, D., Zehelein, J., Steen, H., Pribe, R., Zeller, R., Lehrke, S., Zugck, C., Ivandic, B. T., Katus, H. A. Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene. BMC Med. Genet. 9: 95, 2008.
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Lyophilized
- 
                                            Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 
                                            Konzentration
- 500 μg/mL
- 
                                            Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
- 
                                            Lagerung
- 4 °C,-20 °C
- 
                                            Informationen zur Lagerung
- 
                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
- 
                                            
- 
    - 
                                            : "Diastolic dysfunction in spontaneous type 2 diabetes rhesus monkeys: a study using echocardiography and magnetic resonance imaging."    in: BMC cardiovascular disorders, Vol. 15, pp. 59, (2015)         (PubMed).        
 
 
- 
                                            : "Diastolic dysfunction in spontaneous type 2 diabetes rhesus monkeys: a study using echocardiography and magnetic resonance imaging."    in: BMC cardiovascular disorders, Vol. 15, pp. 59, (2015)         (PubMed).        
- 
    - MYBPC3 (Myosin Binding Protein C, Cardiac (MYBPC3))
- 
                                            Andere Bezeichnung
- MYBPC3
- 
                                            Hintergrund
- 
                        Synonyms: Myosin-binding protein C, cardiac-type, Cardiac MyBP-C, C-protein, cardiac muscle isoform, MYBPC3 Tissue Specificity: Red blood cells. Background: The myosin-binding protein C, cardiac-type is a protein that in humans is encode by the MYBPC3 gene. MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. 
- 
                                            Molekulargewicht
- 160 kDa
- 
                                            Gen-ID
- 4607
- 
                                            UniProt
- Q14896
 Target
- 
                    
 
                                     
                                     
                                    