Kallikrein 1 Antikörper (AA 25-262)
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- Target Alle Kallikrein 1 (KLK1) Antikörper anzeigen
- Kallikrein 1 (KLK1)
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Bindungsspezifität
- AA 25-262
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Kallikrein 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
- Rabbit IgG polyclonal antibody for Kallikrein 1 detection. Tested with WB, ELISA(Cap) in Human.
- Immunogen
- E. coli-derived human Kallikrein 1 recombinant protein (Position: I25-S262).
- Top Product
- Discover our top product KLK1 Primärantikörper
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- Applikationshinweise
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
ELISA(Cap), 1-5 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." in: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).
: "Dynamic involvement of ATG5 in cellular stress responses." in: Cell death & disease, Vol. 5, pp. e1478, (2014) (PubMed).
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Genistein improves inflammatory response and colonic function through NF-κB signal in DSS-induced colonic injury." in: Oncotarget, Vol. 8, Issue 37, pp. 61385-61392, (2017) (PubMed).
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- Target
- Kallikrein 1 (KLK1)
- Andere Bezeichnung
- KLK1 (KLK1 Produkte)
- Synonyme
- KLKR antikoerper, Klk6 antikoerper, hK1 antikoerper, klkr antikoerper, kallikrein antikoerper, 0610007D04Rik antikoerper, Kal antikoerper, Klk1b6 antikoerper, mGk-6 antikoerper, kallikrein 1 antikoerper, kallikrein 1 L homeolog antikoerper, KLK1 antikoerper, klk1.L antikoerper, LOC100101620 antikoerper, Klk1 antikoerper
- Hintergrund
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Synonyms: Kallikrein-1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein, KLK1
Tissue Specificity: Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.
Background: KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
- UniProt
- P06870
- Pathways
- Komplementsystem
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