IL18BP Antikörper (AA 29-193)

Produktnummer ABIN5692876

Der Kaninchen Polyklonal Anti-IL18BP-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, IL18BP in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für IL18BP Antikörper (AA 29-193) (ABIN5692876)

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL18BP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL18BP Antikörper

Bindungsspezifität: AA 29-193

Verwendungszweck: Anti-IL18 binding protein/Il18bp Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-IL18 binding protein/Il18bp Antibody Picoband® (ABIN5692876). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL
ELISA (Cap), 1-5 μg/mL
1. "Entrez Gene: IL18BP interleukin 18 binding protein". 2. Novick D, Kim SH, Fantuzzi G, Reznikov LL, Dinarello CA, Rubinstein M (Mar 1999). "Interleukin-18 binding protein: a novel modulator of the Th1 cytokine response". Immunity. 10 (1): 127-36.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu IL18BP

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Andere Bezeichnung: Il18bp

Hintergrund:

Synonyms: Interleukin-18-binding protein, IL-18BP, Interferon gamma-inducing factor-binding protein, Il18bp, Igifbp

Tissue Specificity: Ubiquitous.

Background: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 43 kDa

Gen-ID: 16068

UniProt: Q9Z0M9