C7 Antikörper (AA 233-453)

Produktnummer ABIN5692807

Der Kaninchen Polyklonal Anti-C7-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, C7 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für C7 Antikörper (AA 233-453) (ABIN5692807)

Target: C7 (Complement Component C7 (C7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-C7 Antikörper

Bindungsspezifität: AA 233-453

Verwendungszweck: Anti-Complement C7 Antibody Picoband®

Marke: Picoband™

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Complement C7 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human Complement C7 recombinant protein (Position: R233-D453).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Barroso, S., Rieubland, C., Alvarez, A. J., Lopez-Trascasa, M., Bart, P.-A., Nunez-Roldan, A., Sanchez, B. Molecular defects of the C7 gene in two patients with complement C7deficiency. Immunology 118: 257-260, 2006. 2. Coto, E., Martinez-Naves, E., Dominguez, O., DiScipio, R. G., Urra, J. M., Lopez-Larrea, C.DNA polymorphism and linkage relationship of the human complement component C6,C7, and C9 genes. Immunogenetics 33: 184-187, 1991.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu C7

Target: C7 (Complement Component C7 (C7))

Andere Bezeichnung: C7

Hintergrund:

Synonyms: Complement component C7, C7

Tissue Specificity: Widely expressed.

Background: This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency.

Molekulargewicht: 93 kDa

Gen-ID: 730

UniProt: P10643

Pathways: Komplementsystem