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Betacellulin Antikörper (AA 32-177)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Betacellulin in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Maus und Ratte.
Produktnummer ABIN5692803

Kurzübersicht für Betacellulin Antikörper (AA 32-177) (ABIN5692803)

Target

Alle Betacellulin (BTC) Antikörper anzeigen
Betacellulin (BTC)

Reaktivität

  • 53
  • 37
  • 12
  • 2
  • 2
  • 1
Maus, Ratte

Wirt

  • 75
  • 7
  • 1
  • 1
Kaninchen

Klonalität

  • 78
  • 6
Polyklonal

Konjugat

  • 45
  • 12
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Betacellulin Antikörper ist unkonjugiert

Applikation

  • 76
  • 29
  • 20
  • 19
  • 16
  • 13
  • 13
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Bindungsspezifität

    • 15
    • 9
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    AA 32-177

    Verwendungszweck

    Anti-Betacellulin/Btc Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Betacellulin/Btc Antibody Picoband® (ABIN5692803). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogen

    E. coli-derived rat Betacellulin recombinant protein (Position: D32-A177).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot,0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section),0.5-1 μg/mL
    ELISA,0.1-0.5 μg/mL
    1. Elbein SC, Wang X, Karim MA, et al. (2006). "Analysis of coding variants in the betacellulin gene in type 2 diabetes and insulin secretion in African American subjects.". BMC Med. Genet. 7: 62. 2. Kim HS, Shin HS, Kwak HJ, Cho CH, Lee CO, Koh GY (February 2003). "Betacellulin induces angiogenesis through activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase in endothelial cell". FASEB J. 17 (2): 318-20.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Betacellulin (BTC)

    Andere Bezeichnung

    Btc

    Hintergrund

    Synonyms: Betacellulin

    Tissue Specificity: Highly expressed in testis.

    Background: Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

    Molekulargewicht

    26 kDa

    Gen-ID

    64022

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
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