Adipsin Antikörper (AA 26-253)
Kurzübersicht für Adipsin Antikörper (AA 26-253) (ABIN5692792)
Target
Alle Adipsin (CFD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 26-253
-
Verwendungszweck
- Anti-Factor D/CFD Antibody Picoband®
-
Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
-
Produktmerkmale
- Anti-Factor D/CFD Antibody Picoband® (ABIN5692792). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
Immunogen
- E. coli-derived human Factor D recombinant protein (Position: I26-A253).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Biesma, D. H., Hannema, A. J., van Velzen-Blad, H., Mulder, L., van Zwieten, R., Kluijt, I., Roos, D. A family with complement factor D deficiency. J. Clin. Invest. 108: 233-240, 2001. 2. Ronti T, Lupattelli G, Mannarino E (April 2006). "The endocrine function of adipose tissue: an update". Clin. Endocrinol. (Oxf) 64 (4): 355-65. 3. Volanakis JE, Narayana SV (April 1996). "Complement factor D, a novel serine protease". Protein Sci. 5 (4): 553-64. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Konzentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Adipsin (CFD) (Complement Factor D (CFD))
-
Andere Bezeichnung
- CFD
-
Hintergrund
-
Synonyms: Complement factor D, Adipsin, C3 convertase activator, Properdin factor D, CFD, DF, PFD
Background: Factor D is a protein which in humans is encoded by the CFD gene. The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. It is also a serine protease that is secreted by adipocytes into the bloodstream. And it stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology.
-
Molekulargewicht
- 45 kDa
-
Gen-ID
- 1675
-
UniProt
- P00746
-
Pathways
- Komplementsystem
Target
-