WWC1 Antikörper (AA 60-110)

Produktnummer ABIN5690326

Der Kaninchen Polyklonal Anti-WWC1-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, WWC1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für WWC1 Antikörper (AA 60-110) (ABIN5690326)

Target: WWC1 (WW and C2 Domain Containing 1 (WWC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WWC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-WWC1 Antikörper

Bindungsspezifität: AA 60-110

Spezifität: WWC1 antibody is human, mouse and rat reactive. At least three isoforms of WWC1 are known to exist, this antibody will detect all three isoforms.

Aufreinigung: WWC1 antibody is affinity chromatography purified via peptide column.

Immunogen: WWC1 antibody was raised against an 18 amino acid peptide near the amino terminus of human WWC1.

The immunogen is located within amino acids 60 - 110 of WWC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WWC1 antibody can be used for detection of WWC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: WWC1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: WWC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu WWC1

Target: WWC1 (WW and C2 Domain Containing 1 (WWC1))

Andere Bezeichnung: WWC1

Hintergrund: The WW and C2 domain containing 1 (WWC1) protein, also known as KIBRA, possesses two WW domains and an internal C2-like domain (1). WWC1 was originally identified as a memory performance-associated protein in humans (2) and has recently been shown to be a novel regulator of the Hippo pathway (3). WWC1 is phosphorylated by the mitotic kinases Aurora-A and -B (4), and in turn activates the Aurora kinases and is required for precise chromosome alignment during mitosis (5).

Molekulargewicht: Predicted: 123 kDa

Observed: 110 kDa

Gen-ID: 23286

NCBI Accession: NP_001155133

UniProt: Q8IX03